see publications on Pubmed


35. L.V. Cappelli*, D. Fiore*, J.M. Phillip*, L. Yoffe*, F. Di Giacomo*, W. Chiu, Y. Hu, C. Kayembe, M. Ginsberg, L. Consolino,J.G.B. Duran, N. Zamponi, A.M. Melnick, F. Boccalatte, W. Tam, O. Elemento, S. Chiaretti, A. Guarini, R. Foà, L. Cerchietti, S. Rafii, G. Inghirami, Endothelial-leukemia interactions remodel drug responses uncovering T-ALL vulnerabilities, 2022, Blood (to appear)

34. J.M. Phillip*, A. Cheetham*, D. Stern*, R. Lin, Y. Li, Y. Wang, D. Rini, H.Cui, J.D. Walston, P.M. Abadir, Nature-inspired delivery of mitochondria-targeted angiotensin receptor blocker, 2022, PNAS Nexus (to appear)

33. F. Cayrol, M. Debernardi, M.V. Revuelta, A. Paulazo, J.M Philip, N. Zamponi, H. Sterle, M. Celeste Díaz Flaqué, C.Magro, J. Ruan, L. Cerchietti, G. Cremaschi, Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma, 2022, Molecular Cancer Therapeutics (in press)

32. A. Sneider, J. H. Kim, A. Kiemen, P-H. Wu, M. Habibi, M. White, J.M. Phillip, L. Gu, D. Wirtz, Deep learning identification of stiffness markers in breast cancer, 2022, Biomaterials

31. M. Clauzure, M.A. Táquez Delgado, J.M. Phillip, M.V. Revuelta, L. Cerchietti, V.A. Medina; Histamine H4 Receptor Agonism Induces Anti-tumor Effects in Human T-Cell Lymphoma, 2022, International Journal of Molecular Sciences


30. E. Gomez de Mariscal, A. Sneider, H. Jayatilaka, J.M. Phillip, D. Wirtz, A. Munoz-Barrutia; Use of the p‐values as a size dependent function to address practical differences when analyzing large datasets, 2021, Scientific Reports

29. M.N. Calvo-Vidal, N. Zamponi, J. Krumsiek, M.A. Stockslager, M.V. Revuelta,  J.M. Phillip, R. Marullo, E. Tikhonova, N. Kotlov, J. Patel, S.N. Yang, L. Yang, T. Taldone, C. Thieblemont, J.P Leonard, P. Martin, G. Inghirami, G. Chiosis, S.R. Manalis, L. Cerchietti, Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas, 2021, Cancer Research

28. N. Kotlov, A. Bagaev, M.V. Revuelta, J.M. Phillip, M.T. Cacciapuoti, Z. Antysheva, V. Svekolkin, E. Tikhonova, N. Miheecheva, N. Kuzkina, G. Nos, F. Tabbo, F. Frenkel, P. Ghione, R. Ataullakhanov, M. Tsiper, N. Almog, N. Fowler, A.M. Melnick, J.P. Leonard, G. Inghirami, L. Cerchietti, Clinical and biological subtypes of B-cell lymphoma revealed by microenvironmental signatures, 2021, Cancer Discovery

27. L. Fontan, R. Goldstein, G. Casalena, M. Durant, M.R. Teater, J. Wilson, J.M. Phillip, M. Xia, S. Shah, I. Us, H. Shinglot, A. Singh, G. Inghirami, A. Melnick, Identification of MALT1 feedback mechanisms enable rational design of potent anti-lymphoma regimens for ABC-DLBCL, 2021, Blood

26. J.M. Phillip, N. Zamponi, M.P. Phillip, J. Daya, S. McGovern, W. Williams, H. Jayatilaka, P-H. Wu, J. Walston, D. Wirtz, Fractional distribution among motility states during ageing, 2021, Communications Biology

25. J.M. Phillip*, Kyu Sang Han*, W.C. Chen, D. Wirtz, P-H. Wu, A robust unsupervised machine learning method to quantify morphological heterogeneity of cells and nuclei, 2021, Nature Protocols


24. N. Yusufova, A. Soshnev, A. Kloetgen, M. Teater, A. Osunsade , J. Camarillo , C.R. Chin, A. Doane, B.J. Venters, S. Portillo-Ledesma, J. Conway, J.M. Phillip, O. Elemento , D. Scott , W. Beguelin , J.D. Licht , N. Kelleher , L. Staudt , A. Skoultchi, M-C. Keogh, E. Apostolou , C. Mason, M. Imielinski , T. Schlick, Y. David , A. Tsirigos , D. Allis, E. Cesarman, A.M. Melnick, Histone 1 deficiency drives lymphoma through disruption of 3D chromatin architecture2020, Nature

23. L. Venturutti,  M. Teater, A. Zhai, A. Chadburn,  L. Babiker,  D. Kim, W. Beguelin,  T.C. Lee,  Y. Kim, C.R. Chin, W.T. Yewdell, B. Raught, J.M. Phillip,  Y. Jiang,  L.M. Staudt,  M.R. Green,  J. Chaudhuri, O. Elemento, P. Farinha, A.P. Weng, M.D. Nissen, C. Steidl,  R.D. Morin, D.W. Scott, G.G. Prive, A.M. Melnick, TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate, 2020, Cell

22. D. Fiore, L.V. Cappelli, P. Zumbo, J.M. Phillip, Z. Liu, S. Cheng, L. Yoffe, P. Ghione, F. Di Maggio, A. Dogan, I. Khodos, E. de Stanchina, J. Casano, W. Tam, D. Betel, L. Cerchietti, R. Rabadan, S. Horowitz, D. Weinstock, G. Inghirami, A novel JAK1 mutant Breast Implant Associated – Anaplastic Large Cell Lymphoma Patient Derived Xenograft to foster preclinical discoveries, 2020, Cancers

21. W. Béguelin, M. Teater, C. Meydan, K.B. Hoehn, J.M. Phillip, A.A. Soshnev, L. Venturutti, M.T. Calvo-Fernández, H. Shen, J.M. Camarillo, N.L. Kelleher, C.E. Mason, O. Elemento, C.D Allis, S.H. Kleinstein, A.M. Melnick, EZH2 gain of function mutations epigenetically reprograms the humoral immune response to yield a pre-malignant lymphoma niche, 2020, Cancer Cell

20. T. Dalton, E. Doubrovina, D. Pankov, R. Reynolds, A. Selvakumar, T. Vizconde, B. Savalia, V. Dyomin, H. Scholze, C. Weigel, C. Oakes, A. Alonso, O. Elemento, H. Pan, J.M. Phillip, R. O’Reilly, B. Gewurz, E. Cesarman, L. Giulino-Roth; Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to viral directed immunotherapy, 2020, Blood

19. P-H. Wu, D. Gilkes, J.M. Phillip, A. Narkar, T. Cheng, J. Marchand, M-H. Lee, R. Li, D. Wirtz, Single-cell Morphology encodes metastatic potential, 2020, Science Advances


18. T.M. Fernando*, R. Marullo*, B. Pera, J.M. Phillip, S.N. Yang, G. Lundell-Smith, I. Torregroza,  H. Ahn, T.  Evans, G.G.  Privé, M. Hirano, A.M. Melnick, L. Cerchietti, BCL6 evolved to enable stress  tolerance  in  vertebrates  and  is broadly required  by  cancer cells  to  adapt  to  stress, 2019, Cancer Discovery

17. H. Jayatilaka, J.M. Phillip, Slowing the spread of cancer: preventing cell communication to stop metastasis, 2019, Future Medicine


16. J.M. Phillip, N. Zamponi, M.P. Phillip, It’s a numbers game—Density dependent MMP activity mediates cell migration, 2018, Oncotarget

15. Y. Yu, Y.S. Rahmanto, M-H. Lee, P-H. Wu, J.M. Phillip, C-H. Huang, M.I. Vitolo, S. Gaillard, S.S. Martin, D.Wirtz, T-L. Wang, I-M. Shih, Activity of Spleen Tyrosine Kinase regulates motility and invasion through modulating actin dynamics in cancer cells, 2018, Oncogene

14. X. Wei*, M.N. Calvo-Vidal*, S. Chen, G. Wu, M.V. Revuelta, J. Sun, J. Zhang, M.F. Walsh, K.E. Nichols, V. Joseph, C. Snyder, C.M. Vachon, J.D. McKay, S.P. Wang, D.S. Jayabalan, L.M Jacobs, D. Becirovic, R.G. Waller, M. Artomov, A. Viale, J. Patel, J.M.Phillip, S. Chen-Kiang, K. Curtin, M. Salama, D. Atanackovic, R. Niesvizky, O. Landgren, S.L. Slager, L.A. Godley, J. Churpek, J.E. Garber, K.C. Anderson, M.J. Daly, R.G. Roeder, C. Dumontet, H.T. Lynch, C.G. Mullighan, N.J. Camp, K. Offit, R.J. Klein, H. Yu, L. Cerchietti, S.M. Lipkin, Germline KDM1A Mutations Confer Susceptibility to Multiple Myeloma, 2018, Cancer Research

13. B. Pera, J. Krumsiek, R. Marullo, S.E. Assouline, J. Patel, J.M. Phillip, L. Roman-Gonzalez, K.K. Mann, L. Cerchietti, Panobinostat alters B-cell lymphoma metabolism resulting in increased dependency on PI3K activity through the choline pathway, 2018, eBioMedicine


12. H. Jayatilaka, A. Giri, M. Karl, I. Aifuwa, N. Trenton, J.M. Phillip, S. Khatau, D. Wirtz, EB1and cytoplasmic dynein mediate protrusion dynamics for efficient three-dimensional cell migration, 2017, FASEB

11. J.M. Phillip, P-H. Wu, D. Gilkes, W. Williams, S. McGovern, J. Daya, J. Chen, I. Aifuwa, J.S.H. Lee, R. Fang, J. Walston, D. Wirtz, Biophysical and biomolecular determination of cellular age in humans, 2017, Nature Biomedical Engineering

10. F. Cayrol, P. Praditsuktavorn, T.M. Fernando, N. Kwiatkowski, R. Marullo, M.N. Calvo-Vidal, J.M. Phillip, B. Pera, S.N. Yang, K. Takpradit, L. Roman, M. Gaudiano, R. Crescenzo, J. Ruan, G. Inghirami, T. Zhang, G. Cremaschi, N.S. Gray, L. Cerchietti, THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors, 2017, Nature Communications


9. K.M. Stroka, B.S. Wong, M. Shriver, J.M. Phillip, D. Wirtz, A. Kontrogianni, K. Konstantopoulos, Loss of giant obscurins from breast epithelium alters cell mechanobiology and mechanosensitivity, 2016, Oncotarget

8. M.Y. Shah*, E. Martinez-Garcia*, J.M. Phillip, A.B. Chambliss, R. Popovic, T. Ezponda, E.C. Small, C. Will, M.P. Phillip, P. Neri, N.J. Bahlis, D. Wirtz, J.D. Licht, MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents, 2016, Oncogene


7. P-H. Wu*, J.M. Phillip*, S.B. Khatau, W-C. Chen, J. Stirman, S. Roseel, K. Tschudi, J. Van-Patten, M. Wong, S. Gupta, A.S. Baras, A. Maitra, D. Wirtz, Evolution of cellular morpho-phenotypes in cancer metastasis, 2015 Scientific Reports

6. J.M. Phillip*, I. Aifuwa*, J. Walston, D. Wirtz, The Mechanobiology of Aging, 2015, Annual Review of Biomedical Engineering

5. D-H. Kim, B. Li, F. Si, J.M. Phillip, D. Wirtz, S.X. Sun, Volume regulation and shape bifurcation in the cell nucleus, 2015, Journal of Cell Science

4. Y. Yu*, S. Gaillard*, J.M. Phillip, A. Pandey, T-C. Huang, S.M. Pinto, D. Wirtz, T-L. Wang, I-M. Shih, Inhibition of Spleen Tyrosine Kinase potentiates paclitaxel-induced cytotoxicity in ovarian cancer cells through stabilizing microtubules, 2015, Cancer Cell 


3. K.M. Aw Yong, Y. Zeng, D. Vindivich, J.M. Phillip, P-H. Wu, D. Wirtz, and R.H. Getzenberg, Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis ,2013, Journal of Cell Physiology

2. Q. Guo, J.M. PhillipS. Majumdar, P-H. Wu, J. Chen, X. Calderon-Colon, O. Schein, B.J. Smith, M.M. Trexler, D. Wirtz, J. Elisseeff, Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair, 2013, Biomaterials

1. W.C. Chen*, P-H. Wu*, J.M. PhillipS.B. Khatau, J.M. Choi, M.R. Dallas, K. Konstantopoulos, S.X. Sun, J.S. Lee, D. Hodzic, D. Wirtz, Functional interplay between the cell cycle and cell phenotypes, 2013, Integrative Biology


System and device for characterizing cells, D. Wirtz, P-H. Wu, S.B. Khatau, W-C Chen, J.M. Phillip, Z.A. Binder, Y. Tseng, U.S. Patent 8,934,698, issued January 13, 2015.